Stress processing and the symptom cycle
Stress, GABA, and the HPA axis
„ GABA signaling inhibits corticotropin-releasing hormone (CRH) and glutamate signaling stimulates CRH
„ Stress increases CRH secretion, stimulating the hypothalamic pituitary adrenal (HPA) axis and adrenal gland production of cortisol and the catecholamines
„ Chronic stress causes neuroplastic changes in the paraventricular nucleus, decreasing GABA receptor expression and increasing glutamate receptor expression, perpetuating the stress response
Alpha GABA provides a multi-faceted approach to stress management with ingredients to reduce symptoms of anxiousness while supporting a healthy stress response